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Neuroscience

Baylor University Medical Center at Dallas

 
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Skull Base Diseases 

Skull base lesions can be located: 

Intracranially - arising from the meninges, cranial nerves, blood vessels, pituitary gland or brain tissue.

Extracranially - involving the paranasal sinuses, nasal cavity, nasopharynx, parapharyngeal space, infratemporal fossa, and temporal bone.

Lesions also may be located in the orbit, arising from its contents, or at the cranio-cervical spine junction where it can involve the foramen magnum and C1 and C2 vertebrae.

Lesions of the skull base may include:

  • Benign or malignant tumors
  • Vascular processes (aneurysm, arterial venous malformation, cavernous malformation).
  • Congenital disorders (chiari malformation, basilar invagination).
  • Pain syndromes (trigeminal neuralgia).
  • Rheumatological disorders (rheumatoid arthritis C1-C2 subluxation)