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Cancer Care

Baylor University Medical Center at Dallas

Blood Cancer, Acute Lymphocytic Leukemia, Leukemia Cancer, 
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Blood and Marrow Transplant Types 

Baylor Charles A. Sammons Cancer Center offers a comprehensive Blood and Marrow Transplant program to treat hematologic cancer, lymphomas, and other cancer types.

There are six types of Blood and Marrow Transplants:

  • Self-Donated Cells (autologous transplant)
  • Matched Sibling (allogeneic transplant)
  • Unrelated Donors (allogeneic transplant)
  • Half-Matched Donors (allogeneic transplant using haploidentical)
  • Umbilical Cord Blood (allogeneic transplant)
  • Reduce-Intensity Conditioning (allogeneic transplant)

Cells use for transplantation can come from several sources:

  • Peripheral Blood Stem Cells
    Peripheral blood stem cells are collected in a process called apheresis, in which blood from a large vein flows through a central venous catheter to a cell separation machine where it is processed. The machine collects peripheral blood stem cells and the rest of the blood is returned.
  • Bone Marrow
    A small portion of bone marrow – the soft, spongy substance that fills the inner cavities of bones and produces blood – is collected for transplantation, using a needle that passes through the skin and into marrow cavity of the hip bone.
  • Umbilical Cord Blood
    For patients without a related or unrelated match, publicly banked umbilical cord blood can be used to perform allogeneic transplantation. One or two umbilical cord blood units are used to provide blood stem cells for bone marrow recovery after chemotherapy and/or radiation therapy.