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Obesity hypoventilation syndrome (OHS)

Alternative Names

Pickwickian syndrome

Symptoms

The main symptoms of OHS are due to lack of sleep and include:

  • Excessive daytime sleepiness
  • Falling asleep during the day
  • Increased risk for accidents or mistakes at work
  • Depression

Symptoms of low blood oxygen level (chronic hypoxia) can also occur, such as shortness of breath or feeling tired after very little effort.

Exams and Tests

People with OHS are usually very overweight. Symptoms of OHS include:

  • Bluish color in the lips, fingers, toes, or skin (cyanosis)
  • Signs of right-side heart failure (cor pulmonale), such as swollen legs or feet, shortness of breath, or feeling tired after little effort
  • Reddish complexion
  • A short, thick neck and small airway passage in the mouth

Tests to confirm OHS include:

Doctors can tell OHS from obstructive sleep apnea by high carbon dioxide levels in the blood when a person is awake.

References

Murray J, Nadel J. Textbook of Respiratory Medicine. 3rd ed. Philadelphia, Pa: W.B. Saunders Company; 2000:2326-2328.

Moore DP, Jefferson JW. Handbook of Medical Psychiatry. 2nd ed. St. Louis, Mo: Mosby, Inc; 2004:221-223.

Review Date: 8/10/2007
Reviewed By: Allen J. Blaivas, DO, Pulmonary, Critical Care, and Sleep Medicine, Department of Veteran Affairs, VA System, East Orange, NJ. Review provided by VeriMed Healthcare Network.

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