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Chronic obstructive pulmonary disease

Definition

Chronic obstructive pulmonary disease (COPD) is lung disease that makes it difficult to breathe. Most people with COPD have both emphysema and chronic bronchitis.

Alternative Names

COPD; Chronic obstructive airway disease; Chronic obstructive lung disease; Emphysema; Chronic bronchitis

Causes

The leading cause of COPD is smoking. Between 15 - 20% of long-term smokers will develop COPD. Using tobacco for a long time causes lung inflammation and destroys air sacs in the lungs. (In rare cases, non-smokers who lack a protein called alpha-1 anti-trypsin can develop emphysema.)

Other risk factors for COPD are:

  • Exposure to certain gases or fumes in the workplace
  • Exposure to heavy amounts of secondhand smoke and pollution
  • Frequent use of cooking gas without proper ventilation

References

Goldman L, Ausiello D.Goldman: Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders; 2007.

Review Date: 1/18/2008
Reviewed By: Andrew Schriber, MD, FCCP, Specialist in Pulmonary, Critical Care, and Sleep Medicine, Virtua Memorial Hospital, Mount Holly, New Jersey. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission. URAC's accreditation program is the first of its kind, requiring compliance with 53 standards of quality and accountability, verified by independent audit.

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