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Toxic megacolon

Definition

Toxic megacolon is a life-threatening complication of other intestinal conditions that causes rapid widening (dilation) of part of the large intestine within 1 to a few days.

Alternative Names

Toxic dilation of the colon; Megarectum

Causes

This is a complication of inflammatory bowel disease, such as ulcerative colitis and Crohn’s disease, and some infections of the colon. Other forms of megacolon exist and can be congenital (present since birth) or associated with some forms of constipation.

References

Goldman L, Ausiello D. Cecil Textbook of Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007.

Review Date: 11/13/2007
Reviewed By: Christian Stone, M.D., Division of Gastroenterology, Washington University in St. Louis School of Medicine, St. Louis, MO. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission. URAC's accreditation program is the first of its kind, requiring compliance with 53 standards of quality and accountability, verified by independent audit.

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