Sclerosing cholangitis

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Sclerosing cholangitis

Definition

Sclerosing cholangitis is swelling (inflammation) of the bile ducts of the liver without a known cause.

Alternative Names

Primary sclerosing cholangitis

Causes

In this condition, the bile ducts inside and outside the liver become narrowed and scarred. The cause is unknown.

The disease is associated with inflammatory bowel disease (Crohn's disease and ulcerative colitis), and genetic factors may also be responsible. Sclerosing cholangitis occurs more often in men than women. This disorder is rare in children.


Digestive system


Bile pathway

Review Date: 2/20/2008
Reviewed By: Christian Stone, MD, Division of Gastroenterology, Washington University in St. Louis, School of Medicine, St. Louis, MO. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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