Paget’s disease

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Overview	Symptoms	Treatment	Prevention

Paget’s disease

Alternative Names

Osteitis deformans

Symptoms

Bone pain (may be severe and persistent)
Bowing of the legs and other visible deformities
Enlarged head
Fracture
Headache
Hearing loss
Joint pain or stiffness
Neck pain
Reduced height
Skull deformities
Warmth of skin over the affected bone

Note: Most patients have no symptoms.

Exams and Tests

Tests that may indicate Paget's disease include:

Bone scan
Bone x-ray
Elevated markers of bone breakdown (for instance, N-telopeptide)
Elevated serum alkaline phosphatase

This disease may also affect the results of the following tests:

References

Goldman L, Ausiello D.Cecil Textbook of Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007.


X-ray

Review Date: 3/19/2008
Reviewed By: A.D.A.M. Editorial Team: David Zieve, MD, MHA, Greg Juhn, MTPW, David R. Eltz, Kelli A. Stacy, ELS. Previously reviewed by Nancy J. Rennert, M.D., Chief of Endocrinology Diabetes, Norwalk Hospital, Associate Clinical Professor of Medicine, Yale University School of Medicine, New Haven, CT. Review provided by VeriMed Healthcare Network (12/6/2007).

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