Ankylosing spondylitis
Definition
Ankylosing spondylitis is a long-term disease that causes inflammation of the joints between the spinal bones and the joints between the spine and the pelvis. It eventually causes the affected spinal bones to join together.
See also: Arthritis
Alternative Names
Rheumatoid spondylitis; Spondylitis; SpondylarthropathyCauses
The cause of ankylosing spondylitis is unknown, but genes seem to play a role.
The disease most frequently begins between ages 20 and 40, but may begin before age 10. It affects more males than females. Risk factors include a family history of ankylosing spondylitis and male gender.
References
Goldman L, Ausiello DA. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007.
Sidiropoulos PI, Hatemi G, Song IH, et al. Evidence-based recommendations for the management of ankylosing spondylitis: systematic literature search of the 3E Initiative in Rheumatology involving a broad panel of experts and practising rheumatologists. Rheumatology (Oxford). 2008. 47(3):355-61.
Dagfinrud H, Kvien TK, Hagen KB. Physiotherapy interventions for ankylosing spondylitis. Cochrane Database, Syst Rev. 2008. (1):CD002822.
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