Interstitial cystitis (IC)

Definition

Interstitial cystitis is chronic (long-term) inflammation of the bladder wall.

Alternative Names

Cystitis - interstitial; IC

Causes

Interstitial cystitis (IC) is a painful condition caused by inflammation of the tissues of the bladder wall. The cause is unknown. The condition is usually diagnosed by ruling out other conditions (such as sexually transmitted disease, bladder cancer, and bladder infections).

IC is frequently misdiagnosed as a urinary tract infection, and patients often go years without a correct diagnosis. On average, there is about a 4-year delay between the time the first symptoms occur and the diagnosis is made.

More than 700,000 Americans have IC. The condition generally occurs around age 30 to 40, although it has been reported in younger people. Women are 10 times more likely to have IC than men.

References

Nickel JC. Interstitial cystitis: a chronic pelvic pain syndrome. Med Clin North Am. 2004; 88(2): 467-81, xii.

Mattox TF. Interstitial cystitis in adolescents and children: a review.  J Pediatr Adolesc Gynecol. 2004; 17(1): 7-11.

Metts JF. Interstitial Cystitis: Urgency and Frequency Syndrome. Am Fam Physician. 2001 Oct 1;64(7):1199-206.

Walsh PC. Campbell's Urology. 8th ed. St. Louis, Mo: WB Saunders; 2002:631-660.