Secondary systemic amyloidosis
Definition
Secondary systemic amyloidosis is a disorder in which abnormal proteins build up in tissues and organs. Clumps of the abnormal proteins are called amyloids.
Secondary means it occurs because of another disease or situation. For example, this condition occurs along with chronic infection or chronic inflammatory disease.
Systemic means body-wide. For example, a systemic disease affects the entire body.
See also:
Alternative Names
Amyloidosis - secondary systemicCauses
The exact cause is of amyloidosis unknown. You are more likely to develop secondary systemic amyloidosis is you have a long-term infection or inflammation.
This condition may occur along with:
- Ankylosing spondylitis
- Bronchiectasis
- Chronic osteomyelitis
- Cystic fibrosis
- Hairy cell leukemia
- Hodgkin's disease
- Long-term skin abscess and certain ulcers
- Long-term kidney dialysis
- Juvenile chronic arthritis
- Multiple myeloma
- Reiter syndrome
- Rheumatoid arthritis
- Sjogren syndrome
- Systemic lupus erythematosus
- Tuberculosis
References
Goldman L, Ausiello D. Cecil Textbook of Medicine. 22nd ed. Philadelphia, Pa: WB Saunders; 2004.
Kumar V, Abbas AK, Fausto N. Robbins and Cotran Pathologic Basis of Disease. 7th ed. St. Louis, Mo: WB Saunders; 2005.
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