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Gas gangrene

Alternative Names

Tissue infection - Clostridial; Gangrene - gas; Myonecrosis; Clostridial infection of tissues

Symptoms

The site of infection becomes inflamed with a pale-to-brownish-red and very painful tissue swelling. If you press on the swollen tissue with your fingers, you may feel gas as a crackly sensation. The edges of the infected area expand so quickly that changes are visible over a few minutes. The involved tissue is completely destroyed.

Symptoms include:

  • Air under the skin (subcutaneous emphysema)
  • Anxiety
  • Blisters filled with brown-red fluid
  • Drainage from the tissues, foul-smelling brown-red or bloody fluid (serosanguineous discharge)
  • Increased heart rate (tachycardia)
  • Moderate-to-high fever
  • Moderate-to-severe pain around a skin injury
  • Pale skin color, later becoming dusky and changing to dark red or purple
  • Progressive swelling around a skin injury
  • Sweating
  • Vesicle formation, combining into large blisters
  • Yellow color to the skin (jaundice)

Note: Symptoms usually begin suddenly and quickly worsen.

If the condition is not treated, the person can develop a shock-like syndrome with decreased blood pressure (hypotension), kidney failure, coma, and finally death.

Exams and Tests

The person may be in shock. A health care professional might feel air in the tissues (crepitus).

  • Anaerobic tissue and/or fluid culture may reveal Clostridium species
  • Blood culture may grow the bacteria causing the infection
  • Gram stain of fluid from the infected area may show gram-positive rods (Clostridium species) or other bacterial types
  • X-ray, CT scan, or MRI of the area may show gas in the tissues

Review Date: 11/1/2007
Reviewed By: Kenneth M. Wener, MD, Department of Infectious Diseases, Lahey Clinic, Burlington, MA. Review provided by VeriMed Healthcare Network.

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