Progressive supranuclear palsy

Alternative Names

Treatment

The goal of treatment is to control symptoms. There is no known cure for progressive supranuclear palsy.

Levodopa and drugs that block the action of a nervous system chemical called acetylcholine (anticholinergic medications) may temporarily reduce symptoms. These medications are not as effective as they are for Parkinson's disease, however.

Many people with this condition will need around-the-clock care and monitoring as they lose brain functions.

Outlook (Prognosis)

Treatment sometimes can reduce symptoms temporarily, but the condition will get worse. Brain function will decline over time. Death commonly occurs in 5 to 7 years.

Possible Complications

• Blood clot in veins (deep vein thrombosis)
• Lack of control over gaze
• Loss of brain functions over time
• Pneumonia
• Poor nutrition (malnutrition)
• Side effects from medications

When to Contact a Medical Professional

Call your health care provider if you often fall, and if you have a stiff neck/body and vision problems.

Also, call if a loved one has been diagnosed with progressive supranuclear palsy and the condition has declined so much that you can no longer care for the person at home.

References

Goetz CG. Goetz: Textbook of Clinical Neurology. 3rd ed. Philadelphia, Pa: Saunders; 2007.