Angioedema

Alternative Names

Treatment

Mild symptoms may not need treatment. Moderate to severe symptoms may need treatment. Breathing difficulty is an emergency condition.

Cool compresses or soaks can provide pain relief.

Medications used to treat angioedema include:

• Antihistamines
• Anti-inflammatory medicines (corticosteroids)
• Cimetidine (Tagamet)
• Epinephrine
• Terbutaline (a bronchodilator)

If the person has trouble breathing, seek immediate medical help.

See: Breathing difficulties - first aid

At the hospital, a tube may be placed in the throat to keep the airway open.

Outlook (Prognosis)

Angioedema that does not affect the breathing may be uncomfortable, but is usually harmless and goes away in a few days.

Possible Complications

• Anaphylactic reaction
• Life-threatening airway blockage (if swelling occurs in the throat)

When to Contact a Medical Professional

Call your health care provider if:

• Angioedema does not respond to treatment
• It is severe
• You have never had angioedema before

Go to the emergency room or call the local emergency number (such as 911) if you have:

• Abnormal breathing sounds (stridor)
• Difficulty breathing
• Fainting
• Wheezing

References

Kaplan AP. Angioedema. J Am Acad Dermatol. Sept 2005; 53(3): 373-88.

Habif TP. Clinical Dermatology. 4th ed. St. Louis, Mo: Mosby; 2004:129.

Marx J. Rosen’s Emergency Medicine: Concepts and Clinical Practice. 6th ed. St. Louis, Mo: Mosby; 2006:1834-1835.

Temiño VM, Peebles RS Jr. The spectrum and treatment of angioedema. Am J Med. 2008;121:282-286.