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Major depression with psychotic features

Alternative Names

Psychotic depression; Delusional depression

Symptoms

This condition occurs when a depressed person loses touch with reality and hallucinates or has delusions. The symptoms of psychotic depression are a combination of symptoms of depression and psychosis.

The content of the delusions and hallucinations can be consistent with depression. For example, some people hear voices criticizing them, telling them that they are not good enough or evil, or telling them that they don't deserve to live and should kill themselves. Psychotic depression requires immediate medical attention to prevent self-harm or harm to others.

Exams and Tests

Diagnosis involves:

  • Psychiatric evaluation
  • Physical examination
  • Laboratory tests

The health care provider should rule out other medical conditions that can cause the same symptoms (such as reactions to certain drugs).

References

International early psychosis association writing group. International clinical practice guidelines for early psychosis. Br J Psychiatry, 2005;187:s120-s124.

Review Date: 2/6/2008
Reviewed By: Christos Ballas, MD, Attending Psychiatrist, Hospital of the University of Pennsylvania, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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