Morquio syndrome

Alternative Names

Mucopolysaccharidosis type IVA; Galactosamine-6-sulfatase deficiency; Mucopolysaccharidosis type IVB; Beta galactosidase deficiency; MPS IV

Treatment

There is no specific treatment for Morquio syndrome. Symptoms are treated as they occur.

A spinal fusion may prevent irreversible spinal cord injury in persons whose neck bones are underdeveloped.

Support Groups

National MPS Society --www.mpssociety.org

Outlook (Prognosis)

Cognitive function is usually normal in patients with Morquio syndrome.

Bone problems can lead to significant complications. For example, the small bones at the top of the neck may slip and damage the spinal cord, causing paralysis. Surgery to correct such problems should be done if possible.

Cardiac complications may lead to death.

Possible Complications

• Breathing problems
• Heart failure
• Spinal cord damage and possible paralysis
• Vision problems
• Walking problems related to abnormal curvature of the spine and other bone problems

When to Contact a Medical Professional

Call your health care provider if symptoms of Morquio syndrome occur.

References

National Institute of Neurological Disorders and Stroke. Mucolipidoses Fact Sheet. Office of Communications and Public Liaison. Bethesda, MD; Publication No. 03-5115. February 13, 2007.