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Hyperimmunoglobulin E syndrome

Alternative Names

Job syndrome; Hyper IgE syndrome

Treatment

There is no known cure for the condition. The goal of treatment is to control the recurrent infections. Medications include antibiotic treatment. Antifungal agents and antiviral agents are prescribed when appropriate.

Sometimes, surgical drainage of abscesses is needed.

IV gamma globulin may help to build up the immune system temporarily when there are severe infections.

Outlook (Prognosis)

Job syndrome is a lifelong chronic condition. Each new infection requires treatment.

Possible Complications

When to Contact a Medical Professional

Call your health care provider if you are experiencing or observing a collection of the above signs and symptoms.

References

Cohen J, Powderly WG. Infectious Diseases. 2nd ed. New York, NY: Elsevier; 2004.

Hoffman R, Benz EJ, Shattil SS, et al. Hematology: Basic Principles and Practice. 4th ed. Orlando, Fl: Churchill Livingstone; 2005.

Review Date: 7/25/2007
Reviewed By: Donald Accetta, MD, MPH, President, Allergy & Asthma Care, PC, Taunton, MA. Review provided by VeriMed Healthcare Network.

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