The mainstay of treatment is a single dose of penicillin G. Relapse is rare.
If appropriately treated in its early stages, yaws is highly curable. Skin lesions may take several months to heal. If treated in its late stage, significant disfigurement may already be present and may not be fully reversible.
Yaws can be disfiguring and disabling because it may cause gross destruction of the skin and bones. It can also cause deformities of the legs, nose, palate, and upper jaw.
Contact your medical provider if you or your child have a chronic skin or bone lesion and have resided in tropical areas where yaws is known to occur.