Selective deficiency of IgA
Definition
Selective deficiency of IgA is the most common immune deficiency disorder. Persons with this disorder have low or absent blood levels of a special protein called immune globulin A.
Alternative Names
IgA deficiencyCauses
IgA deficiency is inherited, which means it's passed down through families. It may be inherited as an autosomal dominant or autosomal recessive trait. It is found in approximately 1 in 700 individuals of European origin. It is less common in people of other ethnicities.
See also: Celiac disease - sprue
References
Hoffman R, Benz EJ, Shattil SS, et al. Hematology: Basic Principles and Practice. 4th ed. Orlando, Fl: Churchill Livingstone; 2005.
Mandell GL, Bennett JE, Dolin R. Principles and Practice of Infectious Diseases. 6th ed. London: Churchill Livingstone; 2005.
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