Selective deficiency of IgA

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Overview	Symptoms	Treatment	Prevention

Selective deficiency of IgA

Alternative Names

IgA deficiency

Symptoms

Most people with selective IgA deficiency have no symptoms.

Some people with this condition have chronic diarrhea caused by intestinal infections. Some have frequent ear, sinus, and lung infections.

Other symptoms include mouth infections and unexplained asthma or bronchiectasis (a disease in which the small air sacs in the lungs become damaged and enlarge).

Exams and Tests

There may be a family history of IgA deficiency. Tests that may be done include:

References

Azar AE. Evaluation of the adult with suspected immunodeficiency. Am J Med. 2007; 120(9):764-8.

Hoffman R, Benz EJ, Shattil SS, et al. Hematology: Basic Principles and Practice. 4th ed. Orlando, Fl: Churchill Livingstone; 2005.

Mandell GL, Bennett JE, Dolin R. Principles and Practice of Infectious Diseases. 6th ed. London: Churchill Livingstone; 2005.

Morimoto Y. Immunodeficiency Overview. Prim Care. 2008; 35(1):159-7, viii.


Antibodies

Review Date: 5/6/2008
Reviewed By: Stuart I. Henochowicz, MD, FACP. Associate Clinical Professor of Medicine, Division of Allergy, Immunology, and Rheumatology, Georgetown University Medical School. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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