Reye syndrome

Treatment

Specific treatment measures have not been determined. Intensive monitoring of the pressure within the brain, blood gases, and blood pH is required. Treatments may include:

• Fluids by IV to provide electrolytes and glucose
• Steroids to reduce swelling in the brain
• Breathing support (a breathing machine may be needed during a deep coma)

When this illness was more common, charcoal hemoperfusion was used to filter out blood toxins. This treatment was done with some success.

Outlook (Prognosis)

How well a person does depends on the severity of any coma, as well as other factors. The average death rate for patients with Reye syndrome is about 40%.

However, the outcome for those who survive an acute episode is good.

Possible Complications

• Permanent brain damage
• Coma

When to Contact a Medical Professional

Go to the emergency room or call the local emergency number (such as 911) immediately if your child has confusion, lethargy, or other mental changes.

References

Cohen J, Powderly WG. Infectious Diseases. 2nd ed. New York, NY: Elsevier; 2004:310-311.

Goetz, CG. Textbook of Clinical Neurology. 2nd ed. St. Louis, Mo: WB Saunders; 2003: 656-657.

Ferri FF. Ferri’s Clinical Advisor: Instant Diagnosis and Treatment. 2005 ed. St. Louis, Mo: Mosby; 2005:738.

Noble J. Textbook of Primary Care Medicine. 3rd ed. St. Louis, Mo: Mosby; 2001:46-47.