Amitriptyline hydrochloride overdose

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Overview	Symptoms	Treatment

Amitriptyline hydrochloride overdose

Alternative Names

Elavil overdose; Adepril overdose; Endep overdose; Enovil overdose; Trepiline overdose

Symptoms

Airways and lungs
- Slowed, labored breathing
Bladder and kidneys
- Urinary hesitancy
Eyes, ears, nose, and throat
- Blurred vision
- Dry mouth
- Enlarged pupils
Heart and blood
- Low blood pressure
- Rapid heart rate
- Shock
Nervous system
- Agitation
- Coma(sudden onset)
- Convulsions (sudden onset)
- Drowsiness
- Dizziness
- Hallucinations
- Headache
- Inability to concentrate
- Muscle rigidity
- Restlessness
- Seizures
- Stupor (lack of alertness)
- Uncoordinated movement
Stomach and intestines
- Constipation
- Increased appetite
- Weight gain
- Vomiting

References

Woolf AD, Erdman AR, Nelson LS, et al. American Association of Poison Control Centers. Tricyclic antidepressant poisoning: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol. 2007;45(3):203-33.

Review Date: 1/20/2008
Reviewed By: Eric Perez, MD, Department of Emergency Medicine, St. Luke's-Roosevelt Hospital Center, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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