Amitriptyline and Perphenazine overdose

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Overview	Symptoms	Treatment

Amitriptyline and Perphenazine overdose

Alternative Names

Etrafon overdose; Triavil overdose; Triptazine overdose

Symptoms

Airways and lungs
- Breathing - slowed and labored
Bladder and kidneys
- Urinary hesitancy
- Inability to completely empty the bladder
Eyes, ears, nose, throat, and mouth
- Blurred vision
- Enlarged pupils
- Excessive salivation
- Nasal congestion
- Unpleasant taste
Heart and blood
- Irregular heartbeat
- Heartbeat- rapid
- Low blood pressure (severe)
- Shock
Muscles and joints
Nervous system
- Agitation
- Coma
- Convulsions
- Disorientation
- Drowsiness
- Fever
- Hypothermia (body temperature is lower than normal)
- Restlessness
- Seizures
- Stupor (lack of alertness)
- Uncoordinated movement
- Tremor
- Weakness
Reproductive system
- Change in menstrual patterns
Skin
- Itchy skin
- Rash
Stomach and intestines
- Constipation
- Loss of appetite
- Nausea
- Vomiting

References

Woolf AD, Erdman AR, Nelson LS, et al. American Association of Poison Control Centers. Tricyclic antidepressant poisoning: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol. 2007;45(3):203-33.

Review Date: 1/20/2008
Reviewed By: Eric Perez, MD, Department of Emergency Medicine, St. Luke's-Roosevelt Hospital Center, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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