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Simian crease

Definition

A simian crease is a single line that runs across the palm of the hand. People normally have three creases in their palms.

The term "simian crease" is not used much anymore since it tends to have a negative meaning (it refers to monkey or ape). The crease is usually just refered to as a single palmar crease.

Alternative Names

Single palmar crease

Considerations

Strong lines (called palmar flexion creases) appear on the palms of the hands and soles of the feet. The palm normally has three of these creases. But sometimes, the horizontal creases join together to form a single one.

Palmar creases develop while the baby is growing in the womb, usually by the 12th week of gestation.

A single palmar crease appears in approximately 1 out of 30 people. Males are twice as likely as females to have this condition. Some palmar creases indicate problems with development and are associated with disorders like Down syndrome.

Causes

A single palmar crease is often a normal finding. However, it may also be associated with:

Review Date: 5/2/2007
Reviewed By: Daniel Rauch, MD, FAAP, Director, Pediatric Hospitalist Program, Associate Professor of Pediatrics, NYU School of Medicine, New York, NY. Portions reviewed by Robert Hurd, MD, Professor of Endocrinology, Department of Biology, Xavier University, Cincinnati, OH. Reviews provided by VeriMed Healthcare Network.

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