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Simian crease

Alternative Names

Single palmar crease

An infant with a single palmar crease may have other symptoms and signs that, when taken together, define a specific syndrome or condition. Diagnosis of that condition is based on a family history, medical history, and complete physical exam.

Your doctor may ask questions such as:

  • Is there a family history of Down syndrome or other disorder associated with a single palmar crease?
  • Does anyone else in the family have a single palmar crease without other symptoms?
  • Did the mother use alcohol while pregnant?
  • What other symptoms do you have?

Based on the answers to these questions, the medical history, and the results of the physical exam, further testing may be necessary.

Review Date: 5/2/2007
Reviewed By: Daniel Rauch, MD, FAAP, Director, Pediatric Hospitalist Program, Associate Professor of Pediatrics, NYU School of Medicine, New York, NY. Portions reviewed by Robert Hurd, MD, Professor of Endocrinology, Department of Biology, Xavier University, Cincinnati, OH. Reviews provided by VeriMed Healthcare Network.

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